KMID : 0374019940170030245
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Ewha Medical Journal 1994 Volume.17 No. 3 p.245 ~ p.250
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Experimental Study of Ligament Healing in the Synovial Fluid in Rabbits : Intrinsic Healing
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Abstract
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Reports suggesting that the tendon itself could play a significant part in the repair process without provision of microcirculation. To investigate the importance of nutritive environment in the healing of reconstructed tendons, the morphology of
sutured free tendons in the synovial fluid of the knee joint, without resstablishment of microcirculation, was studied in rabbits.
@ES Materials and Methods:
@EN The strip of flexor tendon was harvested and divided 2 pieces and repaired with interrupted suture. The knee joit then opened medially through a small incision and repaired tendon strip was transplanted into the open knee joint. After 2
weeks(n=10),
4 weeks(n=10), 6 weeks (n=10) and 8 weeks(n=10), the sutured tendon was removed from the joint and examined histology and measured tensile strength.
@ES Results:
@EN Macroscopically the surface of all piece was smooth and glistening. Fibroblasts were appeared in the suture gap and produced collagen fiber and after 6 weeks many portions of collagen fibers were maturated. The gain of tensile strength was
proportional to the time till 8 weeks.
The findings indicate that diffusion of nutients may be important for the survival and reconstructed tendon can heal in synovial fluid in the manner of intrinsic healing mechanism without resstablishment of the microcirculation.
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